Product Overview
OP-3633 | T16396 | TargetMol Chemicals
CAS: 2102494-14-2
Smiles: [H][C@@]12CC[C@@](O)(C#CC)[C@@]1(C)C[C@H](c1ccc(cc1)N(C)C)[C@@]1([H])[C@@]2([H])CCC2=CC(=O)CC[C@]12C
Formula: C30H39NO2
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: OP-3633 is an effective and selective steroidal glucocorticoid receptor (GR) antagonist (IC50: 29 nM). OP-3633 shows low progesterone receptor (PR) agonism and androgen receptor (AR) antagonism. It also has an inhibition of GR transcriptional activity.
Molecular Weight: 445, 647
