Product Overview
Opiranserin hydrochloride | T9833 | TargetMol Chemicals
CAS: 1440796-75-7
Smiles: O=C(NCC1(N(C)C)CCOCC1)C2=CC(OC)=C(OCCCC)C(OC)=C2.[H]Cl
Formula: C21H35ClN2O5
Pathway: GPCR/G Protein|||Membrane transporter/Ion channel|||Neuroscience
Target: P2X Receptor|||GlyT|||5-HT Receptor
Receptor: N/A
Bioactivity: Opiranserin (VVZ-149) hydrochloride is a dual antagonist of glycine transporter type 2 (GlyT2) and serotonin receptor 2A (5HT2A), with IC50s of 0.86 and 1.3 μM, respectively. It shows antagonistic activity on rP2X3 (IC50=0.87 μM). It is development as an injectable agent for the treatment of postoperative pain.
Molecular Weight: 430, 97
