Product Overview
Opiranserin | T16399 | TargetMol Chemicals
CAS: 1441000-45-8
Smiles: CCCCOc1c(OC)cc(cc1OC)C(=O)NCC1(CCOCC1)N(C)C
Formula: C21H34N2O5
Pathway: GPCR/G Protein|||Membrane transporter/Ion channel|||Neuroscience
Target: P2X Receptor|||GlyT|||5-HT Receptor|||P2 Receptor
Receptor: N/A
Bioactivity: Opiranserin is a development as an injectable agent for the treatment of postoperative pain. Opiranserin is a non-opioid and non-NSAID analgesic candidate and is a dual antagonist of glycine transporter type 2 (GlyT2) and serotonin receptor 2A (5HT2A) (IC50s: 0.86 and 1.3 μM, respectively). Opiranserin displays antagonistic activity on rP2X3 (IC50=0.87 μM).
Molecular Weight: 394, 512
