Product Overview
ORM-10921 | T28267 | TargetMol Chemicals
CAS: 610782-82-6
Smiles: [H][C@]12N(CCC[C@]1(C)COC)CCc1c2oc2ccccc12
Formula: C18H23NO2
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: ORM-10921 is an α-2c adrenergic receptor antagonist. In the behavioural tests, ORM-10921 displayed potent antidepressant and antipsychotic-like effects in the forced swimming test and prepulse-inhibition models analogously. In the pharmacodynamic microdialysis study, ORM-10921 was found to increase extracellular dopamine levels in prefrontal cortex in the baseline conditions.
Molecular Weight: 285, 387
