Product Overview
Orvepitant maleate | T16406 | TargetMol Chemicals
CAS: 579475-24-4
Smiles: OC(=O)\C=C/C(O)=O.[H][C@@]12CCC(=O)N1CCN(C2)[C@H]1CCN([C@H](C1)c1ccc(F)cc1C)C(=O)N(C)[C@H](C)c1cc(cc(c1)C(F)(F)F)C(F)(F)F
Formula: C35H39F7N4O6
Pathway: GPCR/G Protein|||Neuroscience
Target: Neurokinin receptor
Receptor: N/A
Bioactivity: Orvepitant maleate is an effective, selective, and well-tolerated neurokinin-1 receptor (NK-1) antagonist (pKi: 10.2 for human neurokinin-1 receptor). Orvepitant maleate has the potential for depressive disorder and chronic refractory cough (CRC) treatment. Orvepitant maleate can across the blood-brain barrier.
Molecular Weight: 744, 708
