Product Overview
Pacritinib | T6020 | TargetMol Chemicals
CAS: 937272-79-2
Smiles: C(CN1CCCC1)Oc1ccc2Nc3nccc(n3)-c3cccc(COC\C=C\COCc1c2)c3
Formula: C28H32N4O3
Pathway: Angiogenesis|||Chromatin/Epigenetic|||JAK/STAT signaling|||Stem Cells|||Tyrosine Kinase/Adaptors
Target: FLT|||Tyrosine Kinases|||JAK
Receptor: N/A
Bioactivity: Pacritinib (SB1518) is an effective and specific inhibitor of JAK2 and FLT3 (IC50: 23/22 nM, in cell-free assays).
Molecular Weight: 472, 589
