Product Overview
Pamiparib | T5058 | TargetMol Chemicals
CAS: 1446261-44-4
Smiles: C[C@]12CCCN1Cc1n[nH]c(=O)c3cc(F)cc4[nH]c2c1c34
Formula: C16H15FN4O
Pathway: Chromatin/Epigenetic|||DNA Damage/DNA Repair
Target: PARP
Receptor: N/A
Bioactivity: BGB-290 is an orally active, potent, highly selective PARP inhibitor(IC50 of 0.9 nM and 0.5 nM for PARP1 and PARP2, respectively). It has potent PARP trapping, and capability to penetrate the brain, and can be used for the research of various cancers including the solid tumor
Molecular Weight: 298, 321
