Pancuronium dibromide | T0166

Pancuronium dibromide | T0166 | TargetMol Chemicals

CAS: 15500-66-0

Smiles: [Br-].[Br-].[H][C@@]12C[C@@H]([C@H](OC(C)=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC[C@@]2([H])C[C@H](OC(C)=O)[C@H](C[C@]12C)[N+]1(C)CCCCC1)[N+]1(C)CCCCC1

Formula: C35H60Br2N2O4

Pathway: Neuroscience

Target: AChR

Receptor: N/A

Bioactivity: Pancuronium dibromide, a competitive AChR antagonist (IC50 = 5.5 nM), acts as a skeletal muscle relaxant. Pancuronium dibromide blocking neuromuscular transmission is achieved by competing with acetylcholine for receptor sites on the motor end-plate.

Molecular Weight: 732, 683