Product Overview
Parstatin(human) | TP1965 | TargetMol Chemicals
CAS: 1065755-99-8
Smiles:
Formula: C191H330N64O53S3
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: Cell-permeable peptide cleaved from protease-activated receptor 1 (PAR1) upon receptor activation. Attenuates endothelial cell migration and proliferation (IC50 ~ 3 μM), and induces cell cycle arrest. Promotes activation of caspase-3 and exhibits pro-apoptotic activity in vitro. Inhibits angiogenesis and exhibits cardioprotective activity in vivo.
Molecular Weight: 4467, 29
