Product Overview
Parstatin(mouse) | TP1966 | TargetMol Chemicals
CAS: 1065756-01-5
Smiles:
Formula: C189H326N58O57S3
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: Cell-permeable peptide cleaved from protease-activated receptor 1 (PAR1) upon receptor activation. Attenuates endothelial cell migration and proliferation (IC50 ~ 20 μM), and induces cell cycle arrest. Promotes activation of caspase-3 and exhibits pro-apoptotic activity in vitro. Inhibits angiogenesis and exhibits cardioprotective activity in vivo.
Molecular Weight: 4419, 19