Product Overview
PBIT | T16435 | TargetMol Chemicals
CAS: 2514-30-9
Smiles: Cc1ccc(cc1)-n1sc2ccccc2c1=O
Formula: C14H11NOS
Pathway: Chromatin/Epigenetic
Target: Histone Demethylase|||Histone Methyltransferase
Receptor: N/A
Bioactivity: PBIT inhibits JARID1B histone demethylase (IC50 of about 3 μM). PBIT also inhibits JARID1A and JARID1C (IC50s of 6 μM and 4.9 μM, respectively). PBIT is a specific inhibitor of the Jumonji AT-rich Interactive Domain 1 (JARID1) enzymes .
Molecular Weight: 241, 31
