PD 117588 | T28314

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TMC-T28314
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Product Overview

PD 117588 | T28314 | TargetMol Chemicals

CAS: 99734-97-1

Smiles: CCNCC1CCN(C1)c1c(F)cc2c(c1F)n(cc(C(O)=O)c2=O)C1CC1

Formula: C20H23F2N3O3

Pathway: N/A

Target: N/A

Receptor: N/A

Bioactivity: PD 117588 is a quinolone against bacterial isolates from cancer patients. PD 117558 has a broad antimicrobial spectrum with excellent activity against all Gram-positive isolates (including methicillin-resistant Staphylococcus aureus, coagulase-negative staphylococci, Streptococcus faecalis and Group JK-corynebacteria). PD 117588 is also extremely active against Gram-negative bacilli with the exception of Pseudomonas aeruginosa against which ciprofloxacin was more active. PD 117588 has lower minimal inhibitory concentrations for most organisms tested than either imipenem or ceftazidime.

Molecular Weight: 391, 419

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