PD 122860 | T28321

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TMC-T28321
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Product Overview

PD 122860 | T28321 | TargetMol Chemicals

CAS: 122576-86-7

Smiles: CCOC(=O)C1=C(CS(=O)(=O)c2ccncc2)NC(C)=C(C#N)C1c1ccccc1C(F)(F)F

Formula: C23H20F3N3O4S

Pathway: N/A

Target: N/A

Receptor: N/A

Bioactivity: PD 122860 is a dihydropyridine with calcium channel blocking and sodium channel stimulating properties. In the rat heart, PD 122860 increased left ventricular contractility, decreased coronary resistance and altered the shape of the electrocardiogram T-wave. PD 122860 selectively relaxed potassium-contracted aortic rings and inhibited [3H]nitrendipine binding to rat brain membranes.

Molecular Weight: 491, 49

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