Product Overview
PD 122860 | T28321 | TargetMol Chemicals
CAS: 122576-86-7
Smiles: CCOC(=O)C1=C(CS(=O)(=O)c2ccncc2)NC(C)=C(C#N)C1c1ccccc1C(F)(F)F
Formula: C23H20F3N3O4S
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: PD 122860 is a dihydropyridine with calcium channel blocking and sodium channel stimulating properties. In the rat heart, PD 122860 increased left ventricular contractility, decreased coronary resistance and altered the shape of the electrocardiogram T-wave. PD 122860 selectively relaxed potassium-contracted aortic rings and inhibited [3H]nitrendipine binding to rat brain membranes.
Molecular Weight: 491, 49