Product Overview
PD-161570 | T23127 | TargetMol Chemicals
CAS: 192705-80-9
Smiles: CCN(CC)CCCCNc1ncc2cc(c(NC(=O)NC(C)(C)C)nc2n1)-c1c(Cl)cccc1Cl
Formula: C26H35Cl2N7O
Pathway: Angiogenesis|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors
Target: EGFR|||FGFR|||PDGFR|||Src
Receptor: N/A
Bioactivity: PD-161570 is a potent and ATP-competitive human FGF-1 receptor inhibitor with an IC50 of 39.9 nM and a Ki of 42 nM. PD-161570 also inhibits the PDGFR, EGFR and c-Src tyrosine kinases with IC50 values of 310 nM, 240 nM, and 44 nM, respectively.
Molecular Weight: 532, 51
