PD-89211 | T28349

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TMC-T28349
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Product Overview

PD-89211 | T28349 | TargetMol Chemicals

CAS: 444725-49-9

Smiles: OCc1ccc(cc1Cl)N1CCN(Cc2nc3ccccc3[nH]2)CC1

Formula: C19H21ClN4O

Pathway: N/A

Target: N/A

Receptor: N/A

Bioactivity: PD 89211 is a selective dopamine D4 receptor antagonist with high selectivity for the DA D4.2 receptor (> 800-fold) as compared to other hDA receptor subtypes, rat brain serotonin, and adrenergic receptors. In vitro, PD 89211 reverses quinpirole-induced [3H]thymidine uptake in CHOpro5 cells (IC50 = 2.1 nM).

Molecular Weight: 356, 85

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