Product Overview
PD153035 hydrochloride | T1761 | TargetMol Chemicals
CAS: 183322-45-4
Smiles: Cl.COc1cc2ncnc(Nc3cccc(Br)c3)c2cc1OC
Formula: C16H15BrClN3O2
Pathway: Angiogenesis|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors
Target: EGFR
Receptor: N/A
Bioactivity: PD153035 hydrochloride (ZM 252868; AG 1517) is a effective and selective inhibitor of EGFR (Ki: 5.2 pM, IC50: 29 pM); few influence against FGFR, PGDFR, InsR, CSF-1, and Src.
Molecular Weight: 396, 67