PD158780 | T5410

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TMC-T5410
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Product Overview

PD158780 | T5410 | TargetMol Chemicals

CAS: 171179-06-9

Smiles: CNc1cc2c(Nc3cccc(Br)c3)ncnc2cn1

Formula: C14H12BrN5

Pathway: Angiogenesis|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors

Target: EGFR

Receptor: N/A

Bioactivity: PD 158780 reversibly inhibits auto and transphosphorylation of all four members of the ErbB receptor superfamily: EGFR, ErbB2, ErbB3, and ErbB4 (IC50s: 8Ī¼M, 49 nM, 52 nM, and 52 nM in cell assay).

Molecular Weight: 330, 189

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