Product Overview
PD168393 | T6932 | TargetMol Chemicals
CAS: 194423-15-9
Smiles: Brc1cccc(Nc2ncnc3ccc(NC(=O)C=C)cc23)c1
Formula: C17H13BrN4O
Pathway: Angiogenesis|||Apoptosis|||Autophagy|||Chromatin/Epigenetic|||Cytoskeletal Signaling|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors
Target: Apoptosis|||EGFR|||FGFR|||IGF-1R|||PDGFR|||PKC|||Autophagy
Receptor: N/A
Bioactivity: PD168393 is an irreversible EGFR inhibitor (IC50: 0.70 nM), irreversibly alkylate Cys-773; inactive against PKC, FGFR, PDGFR, and insulin.
Molecular Weight: 369, 222
