Product Overview
PD173074 | T2642 | TargetMol Chemicals
CAS: 219580-11-7
Smiles: CCN(CC)CCCCNc1ncc2cc(c(NC(=O)NC(C)(C)C)nc2n1)-c1cc(OC)cc(OC)c1
Formula: C28H41N7O3
Pathway: Angiogenesis|||Apoptosis|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors
Target: Apoptosis|||EGFR|||VEGFR|||FGFR|||IGF-1R|||Src
Receptor: N/A
Bioactivity: PD173074 is an effective FGFR1 inhibitor (IC50: 25 nM) and also inhibits VEGFR2 (IC50: 100-200 nM) in cell-free assays. The selectivity is higher ~1000-fold for FGFR1 than PDGFR and c-Src.
Molecular Weight: 523, 682
