Product Overview
PD176252 | T16449 | TargetMol Chemicals
CAS: 204067-01-6
Smiles: COc1ccc(nc1)C1(CNC(=O)[C@](C)(Cc2c[nH]c3ccccc23)NC(=O)Nc2ccc(cc2)[N+]([O-])=O)CCCCC1
Formula: C32H36N6O5
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: PD176252 is also an agonist of N-Formyl peptide receptor1/2 (EC50s: 0.31 and 0.66 μM in HL-60 cells). PD176252 is an effective antagonist of neuromedin-B preferring (BB1) and gastrin-releasing peptide-preferring (BB2) receptor (Kis: 0.17 nM and 1 nM for human BB1 and BB2 receptors, and 0.66 nM, 16 nM for Rat BB1 and BB2 receptors, respectively).
Molecular Weight: 584, 677