Product Overview
Pemetrexed disodium hemipenta hydrate | T6226 | TargetMol Chemicals
CAS: 357166-30-4
Smiles: O.O.O.O.O.[Na+].[Na+].[Na+].[Na+].Nc1nc(=O)c2c(CCc3ccc(cc3)C(=O)NC(CCC([O-])=O)C([O-])=O)c[nH]c2[nH]1.Nc1nc(=O)c2c(CCc3ccc(cc3)C(=O)NC(CCC([O-])=O)C([O-])=O)c[nH]c2[nH]1
Formula: C40H48N10Na4O17
Pathway: Apoptosis|||Autophagy|||Cell Cycle/Checkpoint|||DNA Damage/DNA Repair|||Metabolism
Target: Apoptosis|||DHFR|||DNA/RNA Synthesis|||Antifolate|||Autophagy
Receptor: N/A
Bioactivity: Pemetrexed Disodium Hydrate is a new-type antifolate and antimetabolite for TS, DHFR, and GARFT. The Ki of Pemetrexed Disodium Hydrate for TS, DHFR and GARFT is 1.3 nM, 7.2 nM and 65 nM, respectively.
Molecular Weight: 1032, 836
