Product Overview
Pemetrexed | T0189 | TargetMol Chemicals
CAS: 137281-23-3
Smiles: Nc1nc(=O)c2c([nH]cc2CCc2ccc(cc2)C(=O)N[C@@H](CCC(=O)O)C(=O)O)[nH]1
Formula: C20H21N5O6
Pathway: Autophagy|||Cell Cycle/Checkpoint|||DNA Damage/DNA Repair|||Metabolism
Target: DHFR|||DNA/RNA Synthesis|||Antifolate|||Autophagy
Receptor: N/A
Bioactivity: Pemetrexed, a guanine-derived antineoplastic agent, binds to and inhibits the enzyme thymidylate synthase (TS).
Molecular Weight: 427, 41
