Pepluanin A | TN4749

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TMC-TN4749
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Pepluanin A | TN4749 | TargetMol Chemicals

CAS: 670257-89-3

Smiles: C[C@H]1\C=C\C(C)(C)[C@H](OC(=O)c2cccnc2)[C@H](OC(C)=O)[C@@H](OC(C)=O)C(=C)[C@H](OC(C)=O)C2[C@@H](OC(=O)c3ccccc3)[C@@](C)(C[C@]2(O)[C@H]1OC(C)=O)OC(C)=O

Formula: C43H51NO15

Pathway: Membrane transporter/Ion channel|||Neuroscience

Target: P-gp

Receptor: N/A

Bioactivity: Pepluanin A, shows a very high activity for a jatrophane diterpene, outperforming cyclosporin A by a factor of at least 2 in the inhibition of Pgp-mediated daunomycin transport.

Molecular Weight: 821, 9

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