Product Overview
Perindopril erbumine | T1484L | TargetMol Chemicals
CAS: 107133-36-8
Smiles: CC(C)(C)N.N1([C@@H]2[C@H](C[C@H]1C(=O)O)CCCC2)C(=O)[C@@H](N[C@H](C(=O)OCC)CCC)C
Formula: C23H43N3O5
Pathway: Apoptosis|||Endocrinology/Hormones|||Immunology/Inflammation
Target: Apoptosis|||RAAS|||MRP
Receptor: N/A
Bioactivity: Perindopril Erbumine is the tert-butylamine salt of perindopril, the ethyl ester of a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. Upon hydrolysis, perindopril erbumine is converted to its active form perindoprilat, inhibiting ACE and the conversion of angiotensin I to angiotensin II; consequently, angiotensin II-mediated vasoconstriction and angiotensin II-stimulated aldosterone secretion from the adrenal cortex are inhibited and diuresis and natriuresis ensue.
Molecular Weight: 441, 61
