Product Overview
PF-04929113 Mesylate | T4342 | TargetMol Chemicals
CAS: 1173111-67-5
Smiles: CS(O)(=O)=O.CC1(C)Cc2c(c(nn2-c2ccc(C(N)=O)c(NC3CCC(CC3)OC(=O)CN)c2)C(F)(F)F)C(=O)C1
Formula: C26H34F3N5O7S
Pathway: Angiogenesis|||Cytoskeletal Signaling|||JAK/STAT signaling|||Metabolism|||Tyrosine Kinase/Adaptors
Target: HSP|||HER
Receptor: N/A
Bioactivity: PF-04929113 Mesylate, a prodrug of SNX-2112, is an orally available Hsp90 inhibitor (Kd: 41 nM) and also induces Her-2 degradation (IC50: 37 nM).
Molecular Weight: 617, 64