Product Overview
PF-05085727 | T16482 | TargetMol Chemicals
CAS: 1415637-72-7
Smiles: Cn1ncc(-c2nn(C)c3ncnc(N4CCC4)c23)c1-c1ccc(cc1)C(F)(F)F
Formula: C20H18F3N7
Pathway: Metabolism
Target: PDE
Receptor: N/A
Bioactivity: PF-05085727 inhibits PDE2A >4, 000-fold selectivity over PDE1 and PDE3-11. PF-05085727 is an effective, selective and brain penetrant inhibitor of cGMP-dependent PDE2A (IC50=2 nM) .
Molecular Weight: 413, 408
