Product Overview
PF-05186462 | T8711 | TargetMol Chemicals
CAS: 1235406-03-7
Smiles: Fc1cc(Oc2ccc(cc2-c2ccnnc2)C(F)(F)F)c(Cl)cc1S(=O)(=O)Nc1nncs1
Formula: C19H10ClF4N5O3S2
Pathway: Membrane transporter/Ion channel
Target: Sodium Channel
Receptor: N/A
Bioactivity: PF-05186462 is a potent, state-dependent, subtype selective Nav1.7 inhibitor with IC50 of 21 nM, no significant activity against Nav1.5.
Molecular Weight: 531, 88
