Product Overview
PF-06733804 | T13207 | TargetMol Chemicals
CAS: 1873373-33-1
Smiles: CNC(=O)c1cnc(N)c(O[C@H]2CN(CC2(F)F)C(=O)Cc2ccc(OC(F)(F)F)cc2)c1
Formula: C20H19F5N4O4
Pathway: Tyrosine Kinase/Adaptors
Target: Trk receptor
Receptor: N/A
Bioactivity: PF-06733804 is a potent inhibitor of pan-Trk in cell-based assays (IC50s: 8.4 nM, 6.2 nM, and 2.2 nM for TrkA, TrkB, and TrkC) with anti-hyperalgesic effect.
Molecular Weight: 474, 388
