Product Overview
PF-06807656 | T24623 | TargetMol Chemicals
CAS: T24623
Smiles: O=C(NC(C1=NN(C)N=C1)C)C2=CC(S(=O)(NC3=CC=C(Cl)C=C3)=O)=C(OC)C=C2
Formula: C19H20ClN5O4S
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: PF-06807656 is insensitive to the introduction of the N171D mutation in the ROMK conduction pore that greatly diminishes the activity of other small-molecule inhibitors. PF-06807656 is an effective ROMK inhibitor (Tl+ flux IC50 = 160 nM).
Molecular Weight: 449, 91
