Product Overview
PF-3758309 hydrochloride | T4230 | TargetMol Chemicals
CAS: 1279034-84-2
Smiles: Cl.CN(C)C[C@@H](NC(=O)N1Cc2c(Nc3nc(C)nc4ccsc34)n[nH]c2C1(C)C)c1ccccc1
Formula: C25H31ClN8OS
Pathway: Apoptosis|||Cytoskeletal Signaling
Target: Apoptosis|||PAK
Receptor: N/A
Bioactivity: PF-3758309, also known as PF-03758309, is a PAK4 inhibitor, is also a n orally bioavailable small-molecule inhibitor of p21-activated kinase 4 (PAK4) with potential antineoplastic activity. PAK4 inhibitor PF-03758309 binds to PAK4, inhibiting PAK4 activity and cancer cell growth. PAK4, a serine/threonine kinase belonging to the p21-activated kinase (PAK) family, is often upregulated in a variety of cancer cell types and plays an important role in cancer cell motility, proliferation, and survival.
Molecular Weight: 527, 09
