Product Overview
PF-4191834 | T16503 | TargetMol Chemicals
CAS: 1029317-21-2
Smiles: Cn1nccc1-c1ccc(Sc2cccc(c2)C2(CCOCC2)C(N)=O)cc1
Formula: C22H23N3O2S
Pathway: Metabolism
Target: Lipoxygenase
Receptor: N/A
Bioactivity: PF-4191834 is a noniron chelating and non-redox inhibitor of the 5-Lipoxygenase (5-LOX) with an IC50 of 229 nM. PF-4191834 shows ~300-fold selectivity for 5-LOX over 12-LOX and 15-LOX and displays no activity toward the cyclooxygenase enzymes. PF-4191834
Molecular Weight: 393, 51
