Product Overview
PF 477736 | T6028 | TargetMol Chemicals
CAS: 952021-60-2
Smiles: Cn1cc(cn1)-c1[nH]c2cc(NC(=O)[C@H](N)C3CCCCC3)cc3c2c1cn[nH]c3=O
Formula: C22H25N7O2
Pathway: Angiogenesis|||Apoptosis|||Cell Cycle/Checkpoint|||Chromatin/Epigenetic|||Tyrosine Kinase/Adaptors
Target: c-Fms|||VEGFR|||FGFR|||FLT|||c-RET|||Chk|||CDK|||Src|||Aurora Kinase
Receptor: N/A
Bioactivity: PF-477736 is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (CSF1R), Ret and Yes.
Molecular Weight: 419, 48
