Product Overview
PF-4989216 | T6938 | TargetMol Chemicals
CAS: 1276553-09-3
Smiles: Fc1cc(ccc1-c1c(sc(N2CCOCC2)c1C#N)-c1ncn[nH]1)C#N
Formula: C18H13FN6OS
Pathway: Apoptosis|||PI3K/Akt/mTOR signaling
Target: Apoptosis|||PI3K
Receptor: N/A
Bioactivity: PF-4989216 is a potent and selective PI3K inhibitor with IC50 of 2 nM, 142 nM, 65 nM, 1 nM, and 110 nM for p110α, p110β, p110γ, p110δ, and VPS34, respectively.
Molecular Weight: 380, 4
