Product Overview
PF-543 hydrochloride | T8840 | TargetMol Chemicals
CAS: 1706522-79-3
Smiles: Cl.Cc1cc(CS(=O)(=O)c2ccccc2)cc(OCc2ccc(CN3CCC[C@@H]3CO)cc2)c1
Formula: C27H32ClNO4S
Pathway: Apoptosis|||Autophagy|||GPCR/G Protein
Target: Apoptosis|||S1P Receptor|||Autophagy|||LPL Receptor
Receptor: N/A
Bioactivity: PF-543 inhibits SphK1 with a K(i) of 3.6 nM, is sphingosine-competitive and is more than 100-fold selective for SphK1 over the SphK2 isoform.
Molecular Weight: 502, 07
