Product Overview
PF-562271 besylate | T6177 | TargetMol Chemicals
CAS: 939791-38-5
Smiles: OS(=O)(=O)c1ccccc1.CN(c1ncccc1CNc1nc(Nc2ccc3NC(=O)Cc3c2)ncc1C(F)(F)F)S(C)(=O)=O
Formula: C27H26F3N7O6S2
Pathway: Angiogenesis|||Cell Cycle/Checkpoint|||Cytoskeletal Signaling|||Tyrosine Kinase/Adaptors
Target: FAK|||PYK2|||CDK
Receptor: N/A
Bioactivity: PF-562271 (besylate) is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM, ~10-fold less potent for Pyk2 than FAK and >100-fold selectivity against other protein kinases, except for some CDKs.
Molecular Weight: 665, 66
