Product Overview
PF-562271 hydrochloride | T21768 | TargetMol Chemicals
CAS: 939791-41-0
Smiles:
Formula: C21H20F3N7O3S HCl
Pathway: Angiogenesis|||Cell Cycle/Checkpoint|||Cytoskeletal Signaling|||Tyrosine Kinase/Adaptors
Target: FAK|||PYK2|||CDK
Receptor: N/A
Bioactivity: PF-562271 is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM in cell-free assays, ~10-fold less potent for Pyk2 than FAK and >100-fold selectivity against other protein kinases, except for some CDKs.
Molecular Weight: 543, 95
