Product Overview
PH-797804 | T1974 | TargetMol Chemicals
CAS: 586379-66-0
Smiles: CNC(=O)c1ccc(C)c(c1)-n1c(C)cc(OCc2ccc(F)cc2F)c(Br)c1=O
Formula: C22H19BrF2N2O3
Pathway: Autophagy|||MAPK
Target: p38 MAPK|||Autophagy
Receptor: N/A
Bioactivity: PH-797804 is a pyridinone inhibitor of p38α (IC50: 26 nM, in a cell-free assay); 4-fold more selective versus p38β and does not inhibit JNK2.
Molecular Weight: 477, 306
