Product Overview
PHA-665752 | T6128 | TargetMol Chemicals
CAS: 477575-56-7
Smiles: Cc1[nH]c(\C=C2/C(=O)Nc3ccc(cc23)S(=O)(=O)Cc2c(Cl)cccc2Cl)c(C)c1C(=O)N1CCC[C@@H]1CN1CCCC1
Formula: C32H34Cl2N4O4S
Pathway: Angiogenesis|||Apoptosis|||Autophagy|||Cytoskeletal Signaling|||Tyrosine Kinase/Adaptors
Target: Apoptosis|||VEGFR|||FGFR|||c-Met/HGFR|||Bcr-Abl|||Autophagy
Receptor: N/A
Bioactivity: PHA-665752 is an effective, specific and ATP-competitive c-Met inhibitor (IC50: 9 nM), >50-fold selectivity for c-Met than STKs or RTKs.
Molecular Weight: 641, 61
