Product Overview
PHA-680632 | T6338 | TargetMol Chemicals
CAS: 398493-79-3
Smiles: CCc1cccc(CC)c1NC(=O)N1Cc2[nH]nc(NC(=O)c3ccc(cc3)N3CCN(C)CC3)c2C1
Formula: C28H35N7O2
Pathway: Angiogenesis|||Cell Cycle/Checkpoint|||Chromatin/Epigenetic|||Tyrosine Kinase/Adaptors
Target: FGFR|||PLK|||Aurora Kinase
Receptor: N/A
Bioactivity: PHA-680632 is potent inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 27 nM, 135 nM and 120 nM, respectively. It has 10- to 200-fold higher IC50 for FGFR1, FLT3, LCK, PLK1, STLK2, and VEGFR2/3.
Molecular Weight: 501, 635
