Product Overview
Phellopterin | T3927 | TargetMol Chemicals
CAS: 2543-94-4
Smiles: COc1c2ccoc2c(OCC=C(C)C)c2oc(=O)ccc12
Formula: C17H16O5
Pathway: Membrane transporter/Ion channel|||Neuroscience
Target: GABA Receptor
Receptor: N/A
Bioactivity: Phellopterin is a partial agonist of the central benzodiazepine receptors in vitro. Phellopterin shows a cytotoxic effect on RAW264.7 cell at the concentration from 40 to 400 μM. Phellopterin reduce TNF-alpha-induced VCAM-1 expression through regulation of the Akt and PKC pathway, which contributes to inhibit the adhesion of monocytes to endothelium.
Molecular Weight: 300, 31