Product Overview
Phleomycin | T21498 | TargetMol Chemicals
CAS: 11006-33-0
Smiles: NC1=NC(C(NCC(N)C(N)=O)CC(N)=N)=NC(C(NC(C(O[C@@]2(OC3[C@H](O)[C@@](O)(C(N)=O)[C@@H](O)C(CO)O3)[C@H](C)[C@@H](O)[C@H](O)[C@H](CO)O2)C4=CNC=N4)C(C(O)C(C)C(NC(C(C)=O)C(NCCC5=NC(C6=NC(C(N)=O)=CS6)CS5)=O)=O)=O)=O)=C1
Formula: C48H69N17O20S2
Pathway: Cell Cycle/Checkpoint|||DNA Damage/DNA Repair|||Microbiology/Virology
Target: DNA/RNA Synthesis|||Antibacterial|||Antibiotic
Receptor: N/A
Bioactivity: Phleomycin is one of the anticancer glycopeptide antibiotics which cause DNA cleavage. It is similar to Bleomycin which binds and intercalates DNA to damage the integrity of the double helix.
Molecular Weight: 1268, 29