Phleomycin | T21498

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TMC-T21498
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Phleomycin | T21498 | TargetMol Chemicals

CAS: 11006-33-0

Smiles: NC1=NC(C(NCC(N)C(N)=O)CC(N)=N)=NC(C(NC(C(O[C@@]2(OC3[C@H](O)[C@@](O)(C(N)=O)[C@@H](O)C(CO)O3)[C@H](C)[C@@H](O)[C@H](O)[C@H](CO)O2)C4=CNC=N4)C(C(O)C(C)C(NC(C(C)=O)C(NCCC5=NC(C6=NC(C(N)=O)=CS6)CS5)=O)=O)=O)=O)=C1

Formula: C48H69N17O20S2

Pathway: Cell Cycle/Checkpoint|||DNA Damage/DNA Repair|||Microbiology/Virology

Target: DNA/RNA Synthesis|||Antibacterial|||Antibiotic

Receptor: N/A

Bioactivity: Phleomycin is one of the anticancer glycopeptide antibiotics which cause DNA cleavage. It is similar to Bleomycin which binds and intercalates DNA to damage the integrity of the double helix.

Molecular Weight: 1268, 29

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