PI-103 | T6143

PI-103 | T6143 | TargetMol Chemicals

CAS: 371935-74-9

Smiles: Oc1cccc(c1)-c1nc(N2CCOCC2)c2oc3ncccc3c2n1

Formula: C19H16N4O3

Pathway: Apoptosis|||Autophagy|||DNA Damage/DNA Repair|||PI3K/Akt/mTOR signaling

Target: Apoptosis|||DNA-PK|||PI3K|||mTOR|||Autophagy

Receptor: N/A

Bioactivity: PI-103 is a potent, cell-permeable, ATP-competitive inhibitor of PI3K family members (IC50s: 2/3/3/15/30/23 nM for p110α/β/δ/γ, mTOR, and DNA-PK).

Molecular Weight: 348, 362