Product Overview
PIK-75 hydrochloride | T2287 | TargetMol Chemicals
CAS: 372196-77-5
Smiles: Cl.CN(\N=C\c1cnc2ccc(Br)cn12)S(=O)(=O)c1cc(ccc1C)[N+]([O-])=O
Formula: C16H15BrClN5O4S
Pathway: Apoptosis|||DNA Damage/DNA Repair|||PI3K/Akt/mTOR signaling
Target: Apoptosis|||DNA-PK|||PI3K
Receptor: N/A
Bioactivity: PIK-75 Hydrochloride is a p110α inhibitor with IC50 of 5.8 nM (200-fold more potently than p110β), isoform-specific mutants at Ser773, and also potently inhibits DNA-PK with IC50 of 2 nM in cell-free assays.
Molecular Weight: 488, 74
