Product Overview
Pimodivir HCl | T4377L | TargetMol Chemicals
CAS: 1777721-70-6
Smiles: O.Cl.Cl.OC(=O)[C@H]1C2CCC(CC2)[C@@H]1Nc1nc(ncc1F)-c1c[nH]c2ncc(F)cc12.OC(=O)[C@H]1C2CCC(CC2)[C@@H]1Nc1nc(ncc1F)-c1c[nH]c2ncc(F)cc12
Formula: C40H42Cl2F4N10O5
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: Pimodivir is an inhibitor of influenza virus replication that blocks the PB2 cap-snatching activity of the influenza viral polymerase complex. The cell-based EC50 for VX-787 is 1.6 nM in a cytopathic effect (CPE) assay. VX-787 is active against a diverse panel of influenza A virus strains.
Molecular Weight: 889, 73