Product Overview
Pinoresinol | TN2080 | TargetMol Chemicals
CAS: 487-36-5
Smiles: COc(cc([C@H]1OC[C@@H]2[C@@H](c(cc3)cc(OC)c3O)OC[C@H]12)cc1)c1O
Formula: C20H22O6
Pathway: Apoptosis|||Cell Cycle/Checkpoint|||NF-Κb
Target: Apoptosis|||NF-κB|||CDK|||p53
Receptor: N/A
Bioactivity: Pinoresinol has antiinflammatory, hepatoprotective, and fungicidal activities, it can protect pial microcirculation from I-reperfusion injury, to increase nitric oxide release and to reduce oxidative stress preserving pial blood flow distribution; it may exert pharmacologically interesting effects via modulation of the insulin-like signalling pathway in C.elegans. Pinoresinol causes an upregulation of the CDK inhibitor p21(WAF1/Cip1) both at mRNA and protein levels, inhibits NF-kappaB and activating protein 1 (AP-1).
Molecular Weight: 358, 4