Product Overview
Pirfenidone | T2386 | TargetMol Chemicals
CAS: 53179-13-8
Smiles: Cc1ccc(=O)n(c1)-c1ccccc1
Formula: C12H11NO
Pathway: Immunology/Inflammation|||Microbiology/Virology|||Stem Cells
Target: CCR|||TGF-beta/Smad
Receptor: N/A
Bioactivity: Pirfenidone is an inhibitor for TGF-β production and TGF-β stimulated collagen production. Pirfenidone inhibits fibroblast, epidermal, platelet-derived, and transforming beta-1 growth factors, thereby slowing tumor cell proliferation. This agent also inhibits DNA synthesis and the production of mRNA for collagen types I and III, resulting in a reduction in radiation-induced fibrosis.
Molecular Weight: 185, 226
