Pitavastatin calcium | T2534

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TMC-T2534
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Product Overview

Pitavastatin calcium | T2534 | TargetMol Chemicals

CAS: 147526-32-7

Smiles: [Ca++].OC(CC(O)\C=C\c1c(nc2ccccc2c1-c1ccc(F)cc1)C1CC1)CC([O-])=O.OC(CC(O)\C=C\c1c(nc2ccccc2c1-c1ccc(F)cc1)C1CC1)CC([O-])=O

Formula: C50H46CaF2N2O8

Pathway: Apoptosis|||Autophagy|||Metabolism

Target: Apoptosis|||Mitophagy|||Endogenous Metabolite|||HMG-CoA Reductase|||Autophagy

Receptor: N/A

Bioactivity: Pitavastatin is a potent inhibitor of HMG-CoA reductase (Ki: 1.7 nM). It lowers both total cholesterol and low-density lipoprotein cholesterol in animals and humans. Metabolism of pitavastatin by the cytochrome P450 system is minimal, reducing the risk of drug-drug interactions.

Molecular Weight: 880, 999

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