Product Overview
Pitavastatin calcium | T2534 | TargetMol Chemicals
CAS: 147526-32-7
Smiles: [Ca++].OC(CC(O)\C=C\c1c(nc2ccccc2c1-c1ccc(F)cc1)C1CC1)CC([O-])=O.OC(CC(O)\C=C\c1c(nc2ccccc2c1-c1ccc(F)cc1)C1CC1)CC([O-])=O
Formula: C50H46CaF2N2O8
Pathway: Apoptosis|||Autophagy|||Metabolism
Target: Apoptosis|||Mitophagy|||Endogenous Metabolite|||HMG-CoA Reductase|||Autophagy
Receptor: N/A
Bioactivity: Pitavastatin is a potent inhibitor of HMG-CoA reductase (Ki: 1.7 nM). It lowers both total cholesterol and low-density lipoprotein cholesterol in animals and humans. Metabolism of pitavastatin by the cytochrome P450 system is minimal, reducing the risk of drug-drug interactions.
Molecular Weight: 880, 999