Product Overview
PLX7904 | T6949 | TargetMol Chemicals
CAS: 1393465-84-3
Smiles: CCN(C)S(=O)(=O)Nc1ccc(F)c(C(=O)c2c[nH]c3ncc(cc23)-c2cnc(nc2)C2CC2)c1F
Formula: C24H22F2N6O3S
Pathway: MAPK
Target: Raf
Receptor: N/A
Bioactivity: PLX7904, also known as PB04, is a potent and selective paradox-breaker RAF inhibitor. It is able to efficiently inhibit activation of ERK1/2 in mutant BRAF melanoma cells but does not hyperactivate ERK1/2 in mutant RAS-expressing cells.
Molecular Weight: 512, 54
