Product Overview
PNU-282987 S enantiomer hydrochloride | T22401 | TargetMol Chemicals
CAS: 128311-08-0
Smiles:
Formula: C14H18Cl2N2O
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: (S)-PNU-282987 is the absolute stereochemistry form of PNU-282987. PNU 282987, a potent agonist of α7-containing neuronal nicotinic acetylcholine receptors (nAChRs) with Ki of 26 nM for the rat receptor, has negligible activity against α1β1γδ and α3β4 nAChRs as well as a panel of monoamine, glutamate, muscarinic, and GABA receptors, except 5-HT3 with Ki of 930 nM.
Molecular Weight: 301, 2
