Product Overview
PNU-74654 | T7204 | TargetMol Chemicals
CAS: 113906-27-7
Smiles: Cc1ccc(\C=N\NC(=O)c2ccccc2Oc2ccccc2)o1
Formula: C19H16N2O3
Pathway: Apoptosis|||Cytoskeletal Signaling|||Stem Cells
Target: Apoptosis|||Wnt/beta-catenin
Receptor: N/A
Bioactivity: PNU 74654 binds to β-catenin (Kd = 450 nM), inhibiting its interaction with the transcription factor T cell factor 4 (Tcf4) resulting in disruption of the Wnt signaling pathway.
Molecular Weight: 320, 348